Services for the European Open Science Cloud

Training events

Synergy of experiment and computation in quantitative systems biology

Sunday, June 23, 2019 - 18:00 to Friday, June 28, 2019 - 09:00

Computational methods and biophysical experiments have advanced rapidly in parallel over recent decades, and are now applied widely to gain molecular-level insights on biological systems. The vast majority of biophysical methods report on the behavior of populations of molecules or on the properties of states of a system. Yet a quantitative understanding of biological systems requires a molecular-level description of phenomena that is generally unobtainable from measurements carried out in bulk. Computations carried out on single macromolecules do not necessarily reflect the statistical nature of molecular behaviors or systems that is captured by experiment. Yet computational approaches can be highly valuable for predicting and interpreting experimental results, and for designing critical experiments to test hypotheses. 

BioExcel Summer School on Biomolecular Simulations 2019

Monday, July 1, 2019 - 09:30 to Friday, July 5, 2019 - 14:30

The summer school is intended for researchers (primarily PhD and post-docs) using or planning to use biomolecular modeling and simulation in their everyday research. Familiarity with Linux and some basic knowledge of molecular modelling software is a requirement.

EMBO course on Integrative Structural Biology at Institut Pasteur

Monday, July 8, 2019 - 10:14 to Friday, July 12, 2019 - 10:14

The fourth Course on Integrative Structural Biology, which will take place at the Institut Pasteur from july 8 to july 13, 2019

This course is supported by EMBO (European Molecular Biology Organization). For more information see here
Problems in structural biology today can very often not be solved by one technique alone, but need to be solved by a combination of methods, including NMR, X-ray crystallography, electron microscopy, structural mass spectrometry, and SAXS. The heterogeneous data coming from these methods need to be combined with advanced molecular modeling techniques. The goal of the course is to provide young scientists that have more specialized knowledge in one of the techniques an overview over the broad range of modern structural methods available. Special emphasis will be given to computational approaches to integrate data (such as IMP, ARIA).

BI/EMBL Hinxton - Structural Bioinformatics course

Monday, September 16, 2019 - 12:00 to Friday, September 20, 2019 - 03:45

Structural biology, determining the three-dimensional shapes of biomacromolecules and their complexes, can tell us a lot about how these molecules function and the roles they play within a cell. Bioinformatics data derived from structure determination experiments enables life-science researchers to address a wide variety of questions. For example, it aids the understanding of how mutations in a gene might alter a protein’s shape, disrupt a catalytic site, or alter the binding affinity of a pharmaceutical compound.

This course explores bioinformatics data resources and tools for the interpretation and exploitation of biomacromolecular structures. It will focus on how best to analyse available structural data to gain useful information given specific research contexts. The course content will investigate the impact of genetic variation on structure, predicting protein structure and function, and exploring interactions with other macromolecules as well as with low-MW compounds. Participants will also have an opportunity to explore protein docking using HADDOCK

Services to support FAIR data

Tuesday, September 17, 2019 - 09:00 to 17:00

OpenAIRERDA Europe, FAIRsFAIR and EOSC-hub are happy to announce a series of three workshops, two in April and one in September, called ‘Services to Support FAIR data’.

This is the third workshop.

The purpose of these workshops is to explore how existing infrastructures can work together and understand how to deliver services that support the creation of FAIR research outputs. The three half-day events, tailored to different audiences, will examine the scholarly and research ecosystem, what exists, what could be modified, and will give insights into optimum service provisioning. They will also be a chance to engage experts and audiences on how to turn FAIR data into reality.


EMBO practical course on Practical Integrative Structural Biology

Sunday, November 3, 2019 - 17:00 to Saturday, November 9, 2019 - 22:00

Characterizing the structure of macromolecular complexes is crucial for understanding their function. For many complexes, however, solving their structure using a single structural biology technique is very challenging. Integrative structural biology combines different experimental techniques with computational modeling to build structural models of such challenging complexes.

Application of integrative structural biology requires an in-depth understanding of both different experimental approaches and computational modeling. To provide advanced training in such a highly interdisciplinary skill set, this EMBO Practical Course will teach how to interpret data from major structural biology techniques and how to integrate this data using computational methods. The course location at the Hamburg Unit of the European Molecular Biology Laboratory and the Center for Structural Systems Biology on the DESY campus will provide on-site synchrotron SAXS and MX beamlines for training. Hands-on practicals will use a well-studied model system, for which data from all main structural biology techniques are available.